Breakthrough egg freezing process offers new hope

For those women needing to put off pregnancy due to illness, work, not having a partner or other personal or medical reasons, but desirous of young healthy eggs to fertilize when motherhood beckons them, consider egg preservation.

In 1953 the first (fowl) sperm cryopreservation was reported. In 1986, Australian fertility specialist Dr. Christopher Chen reported the world’s first pregnancy using slow frozen oocytes (eggs) from a British controlled-rate freezer.

For many years doctors recommended a controlled-rate and slow freezing cryopreservation process to store eggs which offered less than exemplary results for women hoping to become pregnant. Prior to 2002, the success rate of live births from frozen eggs was a mere 1-3% globally.

Today however, an innovative new flash-freezing procedure known as Vitrification is on the rise showcasing stellar results at fertility clinics across the globe.

Vitrification is the latest breakthrough in egg freezing. It is a rapid freezing technique in which a high concentration of cryoprotectant (which is like a form of anti-freeze) is used in place of the water in the cell. Now free of ice and crystals, (which in the past had diminished egg survival rates) the resultant egg is now a solid glass-like cell. Eggs can successfully be stored for years. Most doctors seem to agree that this new procedure greatly improves the chances of egg survival during the freezing and subsequent thawing process.

When a woman is ready to use her stored frozen eggs an embryologist will need to inject the hardened shell with a needle carrying sperm for fertilization to occur. This technique is known as ICSI or Intracytoplasmic Sperm Injection.

A female egg is the largest cell in the human body. Containing a large amount of water, the ice crystals that form during a slow freeze can jeopardize the integrity of the cell.

The vitrification process is showing enormous improvement in egg survival rates, fertilization, pregnancies and ultimately births.

As with the formerly widely used slow-freeze cryopreservation technique, resultant chromosomal abnormalities remain consistent with those not using either of these freezing methods.

According to a report from the American Society of Reproductive Medicine’s official journal Fertility and Sterility, “the techniques of vitrification of oocytes and the subsequent warming process being used today are producing results equal to those using fresh oocytes and are, certainly, far superior to those utilizing slow-freezing techniques”.

With major advancements in our knowledge of egg/oocyte preservation, oocyte physiology and new laboratory techniques, the success of egg preservation is rapidly changing.

With egg/oocyte survival rates of over 90% after vitrification and warming, fertilization rates of 75%–90%, pregnancy rates of 32%–65%, and live-birth rates of over 50% , these numbers bring new hope to those who have had to delay pregnancy.

GetPregnant.org