Success rate of in vitro fertilization (IVF)

For many women, the “baby quest” can be an emotionally daunting and costly experience, devoting many years and big bucks to the cause. According to the most recent National Summary and Fertility Clinic Report from the U.S. Department of Health and Human Services Centers for Disease Control and Preventionabout 12% of women of childbearing age in the United States have used an infertility service and the percentage of women who give birth using an infertility aid each year is steadily climbing. When natural methods fail, many women between the ages of 28 and 48 are turning to an assisted reproductive technology technique called In Vitro Fertilization (IVF).

Of the 422 fertility clinics in operation and participating in this report during this time, 134,260 ART cycles were performed resulting in 38,910 births for a success rate of 29%. The majority of women using ART techniques ranged between the ages of 30-39 (68%). Women 40+ made up an additional 21%.

The IVF process begins when a woman stimulates her ovaries by taking an oral medication like Clomidor Serophene to produce or develop eggs. She can also be monitored for natural egg production via ultra-sounds or blood work. Once her egg(s) reach maturation and are potentially viable they are removed during an outpatient medical procedure called follicular aspiration which entails sending a thin needle through the vaginal canal and into each ovary (follicle) containing the egg(s). With the needle connected to a suction apparatus, it removes the egg(s) and fluid from each ovary. Mild cramping may occur for a short period of time.

In lab, the egg(s) and sperm are combined to create an embryo or embryos. Under a watchful eye, technicians monitor the development of the embryo(s) and days later, the most viable one(s) are selected and transferred through the vaginal canal, cervix, and then into the uterus during an outpatient procedure at a doctor’s office, fertility clinic or hospital. If the procedure is successful, a woman will know if she is pregnant within two weeks.

The IVF method has been used successfully in the United States since 1981. Studies support a higher percentage of conception success rates with embryo transfers to the uterus occurring on day 3 and day 5 out of the 1 to 6 day window of opportunity for this procedure.

Many factors come into play in the success of IVF such as age, origin of infertility, ovarian reserve, FSH level, semen attributes, the woman’s response to treatment, general over-all health condition, the use of a woman’s own fresh egg(s), frozen egg(s) or donor egg(s), emotional state, health insurance coverage and monetary concerns.

There are a number of other ART techniques to consider in addition to IVF such as GIFT and ZIFT with the latter being a minimally invasive surgical procedure performed laparoscopically (MIS) with a small incision (2-3cm) made through the abdomen. A woman will gain a better understanding of which procedure(s) she is a better candidate for after consulting with her OB/GYN or fertility specialist.

Although multiple embryo transfers may pose more of a health risk concern for both the mother and babies, studies suggest the rate of successful live births does increase with more than one embryo transfer.

As a woman matures, her viable egg(s) begin to diminish, especially after 40. For these women, there is another option. A donor egg. Studies reflect that even women over 40 may have a 52% success rate using a donor egg. Women who have trouble carrying to term but whose egg(s) are viable may want to consider a surrogate or gestational carrier. The same IVF method would apply to the surrogate.

Additionally, women who have previously been pregnant and/or given birth through natural methods or using ART techniques are known to have a higher chance of conceiving and birthing once again using ART methods.

Couples who are experiencing low sperm count may choose to use Intracytoplasmic Sperm Injection (ICSI) where a single sperm is injected directly into a woman’s egg for a better likelihood of fertilization. This process is used in conjunction with IVF.

The Society for Assisted Reproductive Technology (SART), an organization of ART providers affiliated with the American Society for Reproductive Medicine (ASRM), has been collecting data and publishing annual reports of pregnancy success rates for fertility clinics in the United States and Canada since 1989.

General information on clinics in your area and throughout the U.S. who are members of The Society for Assisted Reproductive Technology (SART) can be obtained by calling 205.978.5000, extension 109.

According to the Advanced Fertility Center of Chicago, the average cost of a single IVF cycle is approximately $9500, not including medications.

If you live in and have health insurance coverage in one of the following 13 states, you may receive partial to full coverage for infertility issues, IVF cycles or ART procedures. Check with your insurance provider as states mandate different infertility coverage such as lifetime infertility treatment benefit caps of $15,000, 1 IVF session or no IVF cycle – but include other treatments like fertility medications or artificial insemination.

Currently, the list includes Arkansas, California, Connecticut, Texas, Hawaii, Illinois, Maryland, Massachusetts, Montana, New York, Ohio, Rhode Island and West Virginia while Florida and other states are currently under consideration for state mandates concerning these types of procedures.

Get Pregnant. Where do you stand statistically?

Recent studies indicate a healthy woman under the age of 35 who has unprotected intercourse on average of twice a week for three months has a 57% chance of conceiving a baby.

Six months of exposure will bring results on average of 72% while one year of baby-making will bring the number to approximately 85% and two years of trying to conceive reaches near 93%. If you are over 35, simply divide the above numbers in half. These are still great numbers!

Let’s talk eggs!

Now, for a bit of information on the life-span of “the egg”–viable and non-viable.

Studies also show a female embryo in the womb of her mother at only 4-5 months has between 6-7 million eggs also called or referred to as “oocytes“, dropping down to 1-2 million by birth. Puberty brings this number down to 300,000 – 500,000.

The menstrual cycle claims several hundred more over the decades of normal periods and by the time a women reaches her mid to late 30′s some studies indicate the number drops to a mere 25,000 eggs remaining in her ovaries.

Once into her 40′s, another study suggests she may have approximately 1.5 % of her original supply remaining. Regardless of which study you choose to agree with, there are usually plenty left after age 35 to consider the odds favorable – possibly between 25,000 and 90,000. Beyond all of this, eggs are also lost through natural cell death, as well.

Throughout the life span of a woman’s eggs the number of genetically viable ones naturally decreases with age and the proper distribution of the genetic contents may be lost or uncertain. Of the genetically abnormal pregnancies, most go on to miscarry in the first or second trimester of pregnancy and of the women who are over 35, there is even a higher risk of miscarriage with normal and/or abnormal pregnancies and several studies suggest women over 40 have a 1 in 3 or 4 chance of miscarriage.

But do not dismay. Many women go on to eventually conceive and deliver healthy babies well into their 40′s.

Seek help. Find additional helpful information and explore adding prenatal supplements to your diet. Always speak to your physician.

There is a plethora of information and ideas, methods and suggestions you may want to ponder and consider utilizing…ovulation predictor kits, ovulation calendars, natural fertility boosters, fertility handbooks, healthy diets chocked-full of greens, pre-natal vitamins months in advance, basal thermometers, best suggested sexual positions to conceive, large quantities of water to keep the body well-hydrated, suggested exercise routines, books on healthy eating, homeopathic remedies, herbal teas, female infertility information, male infertility information, yoga and relaxation techniques, and all the “dos” the “don’ts” and the pitfalls and myths to take in stride all geared to help you get educated, do what is best for you and get pregnant.

And if need be, assisted reproductive technology (or ART) is available across the globe with outstanding results in many categories in this day and age. Much scientific and medical advancement are being developed and cultivated on a regular basis.

Pregnancy after 40

My only child is approaching his 21st Birthday, I’ve been happily married for eight great years and I decide at the ripe age of forty-three; that’s right a 4 and a 3 to embark on the ultimate journey of baby-making once again!

My husband’s AARP application arrived in the mail recently along with his firefighter retirement check – he just turned 50. He barely looks 40. I tell him it’s genetics, he jokes it’s from not having to raise a few kids.

I know how psyched my 20-year-old son is about having a sibling. He has no idea how psyched I am about having a free 20-year-old babysitter!

After years of mulling it over, hours of discussion, passionately over-analyzing the subject with no definitive resolution, questions arise; the brain goes on overload.

Do I really want to start the whole process again? Will we still be able to travel and work?

And what about raising the kid? Public or private school? Minivan or SUV?

Or as my husband says, Lions or Bears fan? Red Wings or Black Hawks? And how much is college going to be in the year 2026? Will we be cashing in the house for two semesters of college?

And who’s the designated babysitter when the free twenty-year-old gets tired of smelly diapers?

Our cat sitter is only $17 a day and that includes two feedings and one litter box clean-up; wonder if she’ll be available! Some other friends recently turned their loving dog-sitter Paula into their Nanny for their two babies.

Grandma Nancy’s out of service. She’s in Michigan helping with 17 grandkids at the over-ripe age of 82.

What if the little one is allergic to the cats? Who goes, the kid or the cats? What if we have multiples? Won’t even go there!

Here’s a horror story. Last time I had a baby my shoe size went up ½ size. If it happens again; so much for my Donald Pliner Snake-skin sandals.

Then there’s the boob issue; will they sag after nursing and droop like half-filled water balloons. I can always get a boob-job after breast-feeding and finance the kid’s college.

What about baby-proofing the house and sleep . . . ah sleep . . . I really enjoy my sleep . . . do I really want to give up the peace and quiet I’ve come to know and love for so many years since my twenty-year-old son last woke me to his final bout of middle of the night tears so many moons ago.

“Yes.” Absolutely. Bring in the troops. I have like 48 eggs left (okay, truth is, research indicates women over 35 have 25,000-90,000 eggs)… so let’s get the show on the road, remember, I’m 43 and counting! Send in the troops at least every other day. Let’s bravely forge ahead, (divide properly) and conquer!

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